Cellular senescence is immunogenic and promotes anti-tumor immunity
Hossein Fallahi
January 11, 2023
Cellular senescence is a stress response that activates innate immune cells, but little is known about its interplay with the adaptive immune system. In This paper, the authors show that senescent cells combine several features that render them highly efficient in activating dendritic cells (DCs) and antigen-specific CD8 T cells.