Fallahi Bioinformatix Lab@2021-2026

MinimuMM-seq- Genome sequencing of circulating tumor cells for minimally invasive molecular characterization of multiple myeloma pathology

Multiple Myeloma (MM) develops from well-defined precursor stages, however, invasive bone marrow (BM) biopsy limits screening and monitoring strategies for patients. A new paper developed a novel approach, MinimuMM-seq, which enables detection of translocations and copy number abnormalities through whole-genome sequencing of highly pure CTCs.