Fallahi Bioinformatix Lab@2021-2024

A new road for effective immune checkpoint blockade in breast cancer?

Immune checkpoint blockade (ICB) has revolutionized the landscape of cancer treatment. Nevertheless, most cancer patients still do not respond to ICB. This paper demonstrates the critical role of eosinophils in ICB response and provides proof-of-principle for eosinophil engagement to enhance ICB efficacy.