Glioblastoma hijacks neuronal mechanisms for brain invasion
Hossein Fallahi
August 01, 2022
New paper
A new paper demonstrated that whole-brain colonization is fueled by glioblastoma cells that lack connections with other tumor cells and astrocytes yet receive synaptic input from neurons. This subpopulation corresponds to neuronal and neural-progenitor-like tumor cell states, as defined by single-cell transcriptomics, both in mouse models and in the human disease.